Synthesis and anti-tumor evaluation of novel hydrazide and hydrazide-hydrazone derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and anti-tumor evaluation of novel hydrazide and hydrazide-hydrazone derivatives.
The reaction of cyclopentanone with cyanoacetylhydrazine gave 2-cyano-2-cyclopentylideneacetohydrazide (1). Treatment of compound 1 with elemental sulphur in the presence of triethylamine afforded 2-amino-5,6-dihydro- -4H-cyclopenta[b]thiophene-3-carbohydrazide (2), which in-turn formed the corresponding intermediate diazonium salt. The latter was coupled with either ethyl cyanoacetate or ethyl...
متن کاملSynthesis and analgesic activity of novel Hydrazide and Hydrazine derivatives
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were pre...
متن کاملSynthesis and analgesic activity of novel Hydrazide and Hydrazine derivatives
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were pre...
متن کاملsynthesis and analgesic activity of novel hydrazide and hydrazine derivatives
the uses of non-steroidal anti-inflammatory drugs (nsaids) are limited by a variety of side effects. so research on preparing new analgesic agents is important. according to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. the final compounds 10a-10e and 15a-15d were prep...
متن کاملSynthesis and Analgesic Activity of Novel Hydrazide and Hydrazine Derivatives
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were prep...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2013
ISSN: 1846-9558,1330-0075
DOI: 10.2478/acph-2013-0004